Cellular & Molecular Biologist – Senior/Principal

Location: Cambridge Salary: Competitive Ref: ALS 2472

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Our client, a contract research organisation in in vitro pre-clinical drug discovery and safety profiling is looking for a Cellular and Molecular Biologist with a strong practical and intellectual background, to play a key role in an additional new cell biology group, which will support an increase in the portfolio of cell lines and cell biology technology in ion channel-focused research, cardiac safety services and custom assays, using native tissue and stem cells.

Suitably experienced candidates will be considered for a line management role.

Role overview:

  • Working with the senior management team to develop and prosecute a strategy to create new cell lines expressing ion channels – and where applicable, appropriate accessory subunits.
  • Provision of technical expertise for the identification and implementation of new ion channel cell biology technologies.
  • Performing hands-on cell biology laboratory work, such as:
    • Conceiving, planning, designing, executing and supervising experiments
    • Protocol authorisation and documentation of study results
    • Presentation of results and recommendations for future strategy
  • Liaison with Electrophysiology team to establish and validate ion channel cell lines of sufficient quality for the provision of assay services to clients.
  • Leading the identification and implementation of new technologies, aiding generation of new cell lines.

Requirements:

  • PhD in Life sciences with demonstrable experience in laboratory research – Or BSc/MSc with significant laboratory research experience. 
  • Demonstrable experience in eukaryotic cell culture and protein expression
  • Expertise in molecular biology and conducting experiments to generate cell-based expression systems, including stable and transient transfection methodology. 
  • Knowledge of cell-based assays or screening assay development using heterologous cell-based expression systems and stem cells. 
  • Experience of working in a busy industrial/commercial laboratory environment is highly desirable
  • Knowledge and/or experience of patch clamp electrophysiology is highly desirable
  • Experience leading scientific teams, developing and implementing experimental research plans is desirable.
  • Strong interpersonal, presentation, time management, organisational and written/ oral communication skills.
  • Excellent attention to detail and ability to record and maintain accurate written records
  • Ability to work in a cooperative team environment.

Agenda only recruits people with integrity, who are honest and trustworthy and who have a great work ethic. To enable us to hire the very best people, we will conduct a comprehensive background and pre-employment screening, which is an essential part of Agenda’s recruitment process.

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